UI researcher leads effort to map protein functions

If understanding the function of various protein molecules is the next frontier of biology and medicine, as many scientists believe, a team headed by a University of Illinois researcher may be leading the way to better mapping of that frontier.

UI biochemistry Professor John Gerlt and colleagues Matthew Jacobson and Patricia Babbitt at the University of California, San Francisco, and Steven Almo at the Albert Einstein College of Medicine in New York have combined computer search techniques and modeling with experimental validation to tease out the function of some of the millions of proteins whose purpose is as yet unknown.

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