Pet Talk | Fighting heart disease in cats

 

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Cats and dogs may occupy similar places in people's hearts, but when it comes to the two species' hearts — and heart disease — there are a lot of differences.

Dr. Ryan Fries, a veterinary cardiologist at the UI Veterinary Teaching Hospital in Urbana, explains some of these differences and how he is working to improve the prospects for afflicted cats.

Different types of heart disease

Chronic valvular disease is the most common type of heart disease in dogs. In it, the valves degenerate and become misshapen, causing them to leak. Occasionally, cats are born with heart-valve disease, but the development of degenerative valvular disease over time, as it occurs in dogs, is not seen in cats.

Hypertrophic cardiomyopathy, on the other hand, accounts for 80 percent of cases of heart disease in domestic cats but is rare in dogs. In this disease, one or several areas of the walls of the heart become abnormally thickened.

"Certain breeds, such as Maine Coon and Ragdoll cats, are genetically predisposed to developing hypertrophic cardiomyopathy, but any cat can develop this disease," Fries said.

Genetic tests are available for predisposed breeds to identify cats that carry the genetic mutation for hypertrophic cardiomyopathy. Cats carrying this mutation should not be bred.

Restrictive cardiomyopathy and dilated cardiomyopathy are rarely seen in cats.

"Dilated cardiomyopathy was actually very common in cats before the 1980s. Then, veterinarians discovered that dilated cardiomyopathy was linked to a taurine deficiency in commercial cat food. Now that taurine is appropriately added to cat food, this problem is quite rare in cats," said Fries.

Different signs of heart disease

Not only do the types of heart disease cats and dogs acquire differ, so too do the clinical manifestations of heart disease.

"Dogs almost always have an audible murmur, meaning it can be detected with a stethoscope by a veterinarian. This is not true in cats," Fries said. "Cats may occasionally have a murmur, but it doesn't always correlate with presence or absence of heart disease. Listening to the heart is not a definitive way to diagnose heart disease."

Radiographs of the chest are also commonly used to diagnose heart disease in dogs but are not as useful in cats.

"We need an echocardiogram to definitively diagnose heart disease in a cat," Fries said.

Symptoms of heart disease in cats can be subtle and non-specific. Owners may notice that their feline friends are hiding more or are less interested in food or generally more lethargic.

Cats are masters at hiding sickness, so any changes in behavior should tip off an owner that something isn't quite right. Cats may also show signs of respiratory distress, such as labored breathing, panting and open-mouth breathing.

Rear-leg lameness may signal heart disease

Because of changes in blood flow and enlargement of the left atrium, cats with heart disease are at increased risk for blood-clot formation within the heart. Pieces of these clots may break off, being swept by the bloodstream to locations distant from the heart (thromboembolism).

The most common site for thromboembolism in cats is the back legs (saddle thrombus). This leads to acute weakness/paralysis and pain in these limbs. Cats showing signs like this should be taken to a veterinarian immediately.

"Bringing your cat for annual examinations and talking to your veterinarian when you notice any changes in your cat's behavior are the best ways to catch heart disease at earlier stages," Fries said. "There are basically two stages of heart disease in cats, and each hold a different prognosis. In the first stage, the cat has confirmed heart disease and is at risk of developing clinical problems. In the later stage, the cat has heart disease as well as clinical problems, such as heart failure or thromboembolism. An echocardiogram with a veterinary cardiologist can determine which stage a cat is in."

Medical management is the mainstay of heart-disease treatment, but medications are generally not started until symptoms have arisen or are imminent.

Seeking answers for heart disease in cats

"There are many unknowns regarding feline heart disease that current research is exploring," Fries said. "Veterinary cardiologists have not defined early indicators that can predict the long-term prognosis or the time frame for disease progression. At Illinois, we are enrolling cats in a study to find markers of disease, so we can make those prognoses with confidence."

The cardiology service at the University of Illinois is also developing a clinical trial of a new drug that can potentially improve functionality of the heart in cats with hypertrophic cardiomyopathy.

The biomarker study is currently accepting subjects. Anyone interested in enrolling their cat in this study may contact Kathryn McConnell, veterinary technician in the cardiology service, at the Veterinary Teaching Hospital at 217-333-5300.

"Heart health is just as vital to cats as it is to dogs, but heart disease is much more difficult to detect in cats. Regular visits to your veterinarian can help protect your cat's heart and overall health," Fries said.

An archive of pet columns from the UI College of Veterinary Medicine is available at vetmed.illinois.edu/petcolumns/. Requests for reprints of this article may be directed to Chris Beuoy at beuoy@illinois.edu.